Author

P. Castillo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Pepe· 2 shared D. Pedro· 2 shared D. T. Nguyen· 2 shared E. J. Sayour· 2 shared E. Ogando-Rivas· 2 shared J. Huang· 2 shared R. Liu· 2 shared S. Qdaisat· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersCancer Biology

A. Pepe

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

mRNA challenge predicts brain cancer immunogenicity and response to checkpoint inhibitors

P. Castillo, E. Ogando-Rivas, H. Geffrard, A. Pepe, R. Liu, D. T. Nguyen, D. Pedro, D. Zhang, A. DeVries, S. Qdaisat, A. Karachi, M. Rahman, F. Weidert, R. Milner, J. Huang, , E. J. Sayour

The paper develops an mRNA vaccine to predict brain tumor response to checkpoint inhibitors by analyzing cytokine release patterns in vitro.

bioRxiv · Mar 18, 2023 · PreprintCancer Biology

Three-Dimensional Bioconjugated Liquid-Like Solid (LLS) Enhance Characterization of Solid Tumor - Chimeric Antigen Receptor T cell Interactions

D. T. Nguyen, R. Liu, E. Ogando-Rivas, A. Pepe, D. Pedro, S. Qdaisat, T. Y. N. Nguyen, J. Lavrador, G. Golde, R. Smolcheck, J. Ligon, L. Jin, H. Tao, A. Webber, S. Phillpot, , W. G. Sawyer

This study uses 3D bioconjugated liquid-like solids to model tumor-immune interactions, showing CAR T cells can infiltrate and kill cancer cells while revealing immune escape mechanisms.

bioRxiv · Feb 17, 2023 · PreprintBioengineering

Distinct genetic pathways define pre-leukemic and compensatory clonal hematopoiesis in Shwachman-Diamond syndrome

A. L. Kennedy, K. C. Myers, J. Bowman, C. J. Gibson, N. D. Camarda, E. M. Furutani, G. M. Muscato, R. H. Klein, K. Ballotti, S. Liu, C. E. Harris, A. Galvin, M. Malsch, D. Dale, J. M. Gansner, , R. C. Lindsley

The paper identifies distinct genetic pathways in Shwachman-Diamond syndrome that lead to pre-leukemic and compensatory clonal hematopoiesis through EIF6 and TP53 mutations.

bioRxiv · Jun 4, 2020 · PreprintCancer Biology