Author

P. D. Aldridge

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Organism:E. coli· 3 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

C. Harding· 2 shared J. Hall· 2 shared A. Albanna· 1 shared A. Ali· 1 shared A. M. Z. Tan· 1 shared A. Tan· 1 shared C. Gillespie· 1 shared C. M. Birchall· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersMicrobiology

C. Harding

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3 papers

Recent·Most cited

Exploring the in-situ evolution of Nitrofurantoin resistance in clinically derived Uropathogenic Escherichia coli isolates.

M. Vallee, C. Harding, J. Hall, P. D. Aldridge, A. Tan

This study investigates the in situ evolution of Nitrofurantoin resistance in uropathogenic E. coli isolates from two UTI patients, finding no fitness advantage for resistant strains but a selective advantage at sub-MIC concentrations.

bioRxiv · Jul 19, 2022Microbiology

Evasion of Toll-like Receptor Recognition by Escherichia coli is mediated via Population Level Regulation of Flagellin Production

M. Lanz, C. M. Birchall, L. K. Drage, D. M. Picton, C. Mowbray, Q. Alsenani, A. M. Z. Tan, A. Ali, C. Harding, R. Pickard, J. Hall, P. D. Aldridge

This study shows that uropathogenic E. coli evades TLR5 recognition by regulating flagellin production at the population level, not through antigenic variation.

bioRxiv · Nov 18, 2021 · PreprintMicrobiology

Driving the expression of the Salmonella enterica sv Typhimurium flagellum using flhDC from Escherichia coli results in key regulatory and cellular differences.

A. Albanna, M. Sim, P. Hoskisson, C. Gillespie, C. V. Rao, P. D. Aldridge

This study replaces E. coli flhDC genes with Salmonella enterica flhDC sequences and finds differences in flagellar gene expression and regulatory mechanisms.

bioRxiv · May 29, 2018Microbiology