Author

P. D. Boudreau

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Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Stornetta· 1 shared E. P. Balskus· 1 shared L. Zha· 1 shared M. R. Wilson· 1 shared P. W. Villalta· 1 shared S. Balbo· 1 shared Y. Jiang· 1 shared

Activity by Year

2019-2019 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

A. Stornetta

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1 paper

Recent·Most cited

The reactivity of an unusual amidase may explain colibactin’s DNA cross-linking activity

Y. Jiang, A. Stornetta, P. W. Villalta, M. R. Wilson, P. D. Boudreau, L. Zha, S. Balbo, E. P. Balskus

This paper identifies ClbL as an amidase enzyme that forms amide bonds, contributing to colibactin's DNA cross-linking activity by incorporating electrophilic warheads into its structure.

bioRxiv · Mar 4, 2019Biochemistry