Protein polyglutamylation catalyzed by the bacterial Calmodulin-dependent pseudokinase SidJ
A. Sulpizio, M. E. Minelli, M. Wan, P. D. Burrowes, X. Wu, E. J. Sanford, J.-H. Shin, B. Williams, M. L. Goldberg, M. B. Smolka, Y. Mao
This study identifies SidJ as a bacterial pseudokinase that catalyzes polyglutamylation of SdeA, a Legionella effector, in a CaM-dependent manner, suppressing ADP-ribosylation.
bioRxiv · Aug 20, 2019Biochemistry