Author

E. J. Sanford

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 4 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Organism:yeast· 2 Organism:bacteria (other)· 1 Approach:biophysical modeling· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

M. B. Smolka· 5 shared A. M. N. Joiner· 1 shared A. Sanchi· 1 shared A. Shami Shah· 1 shared A. Sulpizio· 1 shared B. P. Phillips· 1 shared B. Williams· 1 shared D. Dibitetto· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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5 shared papersCell Biology

M. B. Smolka

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5 papers

Recent·Most cited

Proximity labeling reveals spatial regulation of the anaphase-promoting complex/cyclosome by a microtubule adaptor

X. Cao, A. Shami Shah, E. J. Sanford, M. B. Smolka, J. M. Baskin

This study identifies PLEKHA5 as a microtubule adaptor that spatially regulates APC/C activity during mitosis by facilitating its localization to microtubules and interaction with CDC20.

bioRxiv · Jan 4, 2022Cell Biology

Fork Slowing and Reversal as an Adaptive Response to Chronic ATR Inhibition

D. Dibitetto, A. Sanchi, E. J. Sanford, M. Lopes, M. B. Smolka

This study investigates the effects of chronic low-dose ATR inhibition on replication dynamics, revealing fork reversal as an adaptive response that enhances cell survival and can be exploited to improve cancer therapies.

bioRxiv · May 18, 2021 · PreprintCancer Biology

Structure and mechanism of TRAPPIII-mediated Rab1 activation

A. M. N. Joiner, B. P. Phillips, K. Yugandhar, E. J. Sanford, M. B. Smolka, H. Yu, E. A. Miller, J. C. Fromme

This study determines the cryo-EM structure of the yeast TRAPPIII complex bound to Rab1/Ypt1, revealing that Trs85 anchors the complex to membranes via an amphipathic helix to activate Rab1.

bioRxiv · Oct 8, 2020 · PreprintCell Biology

Protein polyglutamylation catalyzed by the bacterial Calmodulin-dependent pseudokinase SidJ

A. Sulpizio, M. E. Minelli, M. Wan, P. D. Burrowes, X. Wu, E. J. Sanford, J.-H. Shin, B. Williams, M. L. Goldberg, M. B. Smolka, Y. Mao

This study identifies SidJ as a bacterial pseudokinase that catalyzes polyglutamylation of SdeA, a Legionella effector, in a CaM-dependent manner, suppressing ADP-ribosylation.

bioRxiv · Aug 20, 2019Biochemistry

The yeast Art1 arrestin domain contains disordered insertions that regulate its localization and activity

M. G. Baile, E. L. Guiney, E. J. Sanford, J. A. MacGurn, M. B. Smolka, S. D. Emr

The paper identifies loop insertions in the yeast Art1 protein that regulate its localization and activity through phosphorylation and cargo specificity.

bioRxiv · Feb 18, 2019Cell Biology