Author

P. D. Harris

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 5 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:fluorescence / live-cell microscopy· 5 Approach:experimental assay· 3 Research Focus:protein folding & dynamics· 3 Research Focus:cell type annotation· 2 Approach:statistical model· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Organism:human· 1

Frequent Co-Authors

E. Lerner· 5 shared T. Cordes· 2 shared A. Narducci· 1 shared B. Ayler· 1 shared C. Gebhardt· 1 shared C. Potts· 1 shared D. Bair· 1 shared D. Bimczok· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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5 shared papersBiophysics

E. Lerner

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Multiparameter-based photosynthetic state transitions of single phytoplankton cells

P. D. Harris, N. Ben Eliezer, N. Keren, E. Lerner

This study tracks single phytoplankton cell photophysiological states using multi-parameter fluorescence analysis during diurnal cycles and light changes, revealing distinct subpopulations and transitions.

bioRxiv · Dec 31, 2023 · PreprintBiophysics

Single-molecule detection and super-resolution imaging with a portable and adaptable 3D-printed microscopy platform (Brick-MIC)

G. G. Moya Munoz, O. Brix, P. Klocke, P. D. Harris, J. R. Luna Piedra, N. D. Wendler, E. Lerner, N. Zijlstra, T. Cordes

The paper introduces Brick-MIC, an affordable, open-source 3D-printed microscopy platform that enables single-molecule and super-resolution imaging techniques.

bioRxiv · Dec 29, 2023Biophysics

Structural and Dynamic Insights Into α-Synuclein Dimer Conformations

J. Zamel, J. Chen, S. Zaer, P. D. Harris, P. Drori, M. Lebendiker, N. Kalisman, N. V. Dokholyan, E. Lerner

The paper identifies a compact, stable dimeric conformation of α-synuclein that may promote dityrosine linkage and is implicated in Parkinson's disease.

bioRxiv · Oct 21, 2022Biophysics

Identification and Quantification of Within-Burst Dynamics in Singly-Labeled Single-Molecule Fluorescence Lifetime Experiments

P. D. Harris, E. Lerner

This paper introduces an analytical framework to quantify within-burst dynamics in single-molecule fluorescence lifetime experiments, demonstrating its application to -synuclein monomer structural dynamics.

bioRxiv · May 23, 2022Biophysics

MNPmApp: An image analysis tool to quantify mononuclear phagocyte distribution in mucosal tissues

C. Potts, J. Schearer, D. Bair, B. Ayler, J. Love, J. Dankoff, P. D. Harris, D. Zosso, D. Bimczok

The paper develops and validates MNPmApp, a MATLAB-based tool for quantifying mononuclear phagocyte distribution in mucosal tissues using fluorescence microscopy images.

bioRxiv · Sep 27, 2021Immunology

Multi-parameter photon-by-photon hidden Markov modeling

P. D. Harris, A. Narducci, C. Gebhardt, T. Cordes, S. Weiss, E. Lerner

This paper introduces multi-parameter H2MM to distinguish FRET dynamics from photophysical transitions in smFRET data, improving the analysis of biomolecular conformational changes.

bioRxiv · Apr 8, 2021Biophysics