Quaternary structure independent folding of voltage-gated ion channel pore domain subunits
C. Arrigoni, M. Lolicato, D. Shaya, A. Rohaim, F. Findeisen, C. M. Colleran, P. Dominik, S. S. Kim, J. Schuermann, A. A. Kossiakoff, D. L. Minor
This paper shows that voltage-gated ion channel pore domains can maintain their structure without relying on quaternary interactions, revealing new insights into their folding and assembly.
bioRxiv · Aug 15, 2021Biophysics