Author

P. E. Mangeot

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:genome assembly· 1 Research Focus:perturbation response prediction· 1 Research Focus:variant calling· 1

Frequent Co-Authors

E. Verhoeyen· 2 shared A. Corbin· 1 shared A. gutierrez-Guerrero· 1 shared A. Krug· 1 shared A. Marnef· 1 shared C. Pinset· 1 shared D. Hendriks· 1 shared E. Bokobza· 1 shared

Activity by Year

2017-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBioengineering

E. Verhoeyen

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Author profile →

2 papers

Recent·Most cited

Nanoblades allow high-level genome editing in organoids

V. Tiroille, A. Krug, E. Bokobza, M. Bulcaen, M. Ensinck, M. Geurts, D. Hendriks, F. Vermeulen, F. Larbret, A. gutierrez-Guerrero, M. Louise, R. Gijsbers, P. E. Mangeot, H. Clevers, M. Carlon, , E. Verhoeyen

This paper introduces nanoblade technology for efficient, low-toxicity genome editing in organoids, achieving up to 80% gene knockout in murine and human organoids.

bioRxiv · Aug 4, 2022 · PreprintBioengineering

Efficient genome editing in primary cells and in vivo using viral-derived "Nanoblades" loaded with Cas9/sgRNA ribonucleoproteins

P. E. Mangeot, V. Rissons, F. Fusil, A. Marnef, E. Laurent, J. Blin, V. Mournetas, E. Massourides, T. J. M. Sohier, A. Corbin, F. Aube, C. Pinset, L. Schaeffer, G. Legube, F.-L. Cosset, , E. P. Ricci

bioRxiv · Oct 12, 2017Cell Biology