Author

G. Legube

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cell Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

A. Batut· 1 shared A. Corbin· 1 shared A. Dortignac· 1 shared A. Loffreda· 1 shared A. Marnef· 1 shared A. Montagner· 1 shared A. Polizzi· 1 shared A. Yart· 1 shared

Activity by Year

2017-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperPathology

A. Batut

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Chromatin organization drives the exploration strategy of nuclear factors

M. Mazzocca, A. Loffreda, E. Colombo, T. Fillot, D. Gnani, P. Falletta, E. Monteleone, S. Capozi, E. Bertrand, G. Legube, Z. Lavagnino, C. Tacchetti, D. Mazza

This study shows how nuclear factors explore chromatin by balancing diffusion and dense region sampling, with implications for p53 function and nuclear organization.

bioRxiv · Dec 29, 2022 · PreprintBiophysics

Nuclear HMGB1 protects from non-alcoholic fatty liver diseases through negative regulation of liver X receptor

J. Personnaz, E. Piccolo, A. Dortignac, J. S. Iacovoni, J. Mariette, A. Polizzi, A. Batut, S. Deleruyelle, R. Paccoud, E. Moreau, F. Martins, T. Clouaire, F. Benhamed, A. Montagner, W. A. Wahli, , J.-P. Pradere

This study shows that nuclear HMGB1 suppresses liver lipogenesis in NAFLD by inhibiting LXR activity, preventing steatosis and insulin resistance.

bioRxiv · Feb 17, 2021 · PreprintPathology

Efficient genome editing in primary cells and in vivo using viral-derived "Nanoblades" loaded with Cas9/sgRNA ribonucleoproteins

P. E. Mangeot, V. Rissons, F. Fusil, A. Marnef, E. Laurent, J. Blin, V. Mournetas, E. Massourides, T. J. M. Sohier, A. Corbin, F. Aube, C. Pinset, L. Schaeffer, G. Legube, F.-L. Cosset, , E. P. Ricci

bioRxiv · Oct 12, 2017Cell Biology