Author

L. Schaeffer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

I. Scionti· 2 shared A. Corbin· 1 shared A. Garcia· 1 shared A. Ghasemizadeh· 1 shared A. Guiraud· 1 shared A. Hamiche· 1 shared A. Marnef· 1 shared A. Osseni· 1 shared

Activity by Year

2017-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersPhysiology

I. Scionti

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Pharmacological inhibition of HDAC6 downregulates TGF-β via Smad2/3 acetylation and improves dystrophin-deficient muscles.

A. Osseni, A. Ravel-Chapuis, I. Scionti, Y.-G. Gangloff, V. Moncollin, R. Mounier, P. Leblanc, B. J. Jasmin, L. Schaeffer

This study shows that inhibiting HDAC6 with tubastatin A improves dystrophin-deficient muscle by reducing fibrosis and restoring microtubules and NMJ through Smad2/3 acetylation and TGF-β signaling inhibition.

bioRxiv · Jan 21, 2022 · PreprintPhysiology

H2A.Z is dispensable for both basal and activated transcription in post-mitotic mouse muscles

E. Belotti, N. Lacoste, T. Simonet, C. Papin, K. Padmanabhan, L. Ramos, D. Dalkara, I. Scionti, A. Hamiche, S. Dimitrov, L. Schaeffer

This study shows H2A.Z is not required for transcription in post-mitotic muscle cells, challenging its role as an activator and suggesting it is a marker of active promoters.

bioRxiv · Oct 30, 2019Cell Biology

Muscle MACF1 maintains myonuclei and mitochondria localization through microtubules to control muscle functionalities

A. Ghasemizadeh, E. Christin, A. Guiraud, N. Couturier, V. Risson, E. Girard, C. Soler, L. Laddada, K. Jagla, C. Sanchez, F.-I. Jaque-Fernandez, A. Garcia, M. Lanfranchi, V. Jacquemond, J. Gondin, , V. Gache

This study identifies MACF1 as a regulator of myonuclei and mitochondria positioning in muscle through microtubules, affecting muscle function and disease.

bioRxiv · May 15, 2019Cell Biology

Efficient genome editing in primary cells and in vivo using viral-derived "Nanoblades" loaded with Cas9/sgRNA ribonucleoproteins

P. E. Mangeot, V. Rissons, F. Fusil, A. Marnef, E. Laurent, J. Blin, V. Mournetas, E. Massourides, T. J. M. Sohier, A. Corbin, F. Aube, C. Pinset, L. Schaeffer, G. Legube, F.-L. Cosset, , E. P. Ricci

bioRxiv · Oct 12, 2017Cell Biology