Cancer BiologybioRxiv
Targeted CRISPR screening identifies PRMT5 as synthetic lethality combinatorial target with gemcitabine in pancreatic cancer cells
X. Wei, J. Yang, S. J. Adair…·M. Adli
The paper identifies PRMT5 as a synthetic lethal target with gemcitabine in pancreatic cancer using CRISPR screening in a PDX model.
DOI 10.1073/pnas.2009899117