Author

M. Adli

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Assay:Hi-C· 1

Frequent Co-Authors

J. Yang· 2 shared X. Wei· 2 shared A. Daneshkhah· 1 shared A. Dutta· 1 shared A. H. Habieb· 1 shared C. Kuscu· 1 shared D. Liu· 1 shared E. L. Aiden· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBioengineering

J. Yang

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Depletion of lamins B1 and B2 alters chromatin mobility and induces differential gene expression by a mesoscale-motion dependent mechanism

E. M. Pujadas, X. Wei, N. Acosta, L. Carter, J. Yang, L. Almassalha, A. Daneshkhah, S. S. P. Rao, V. Agrawal, F. Seker-Polat, E. L. Aiden, M. T. Kanemaki, V. Backman, M. Adli

This study shows that depleting lamins B1 and B2 changes chromatin mobility and gene expression through mesoscale-motion dependent mechanisms.

bioRxiv · Jun 26, 2023 · PreprintBioengineering

Targeted CRISPR screening identifies PRMT5 as synthetic lethality combinatorial target with gemcitabine in pancreatic cancer cells

X. Wei, J. Yang, S. J. Adair, C. Kuscu, K. Y. Lee, W. Kane, P. E. O'Hara, D. Liu, Y. M. Demirlenk, A. H. Habieb, E. Yilmaz, A. Dutta, T. Bauer, M. Adli

The paper identifies PRMT5 as a synthetic lethal target with gemcitabine in pancreatic cancer using CRISPR screening in a PDX model.

bioRxiv · May 25, 2020Cancer Biology