Cas13b is a Type VI-B CRISPR-associated RNA-Guided RNase differentially regulated by accessory proteins Csx27 and Csx28
A. Smargon, D. B. T. Cox, N. Pyzocha, K. Zheng, I. M. Slaymaker, J. S. Gootenberg, O. A. Abudayyeh, P. Essletzbichler, S. Shmakov, K. S. Makarova, E. V. Koonin, F. Zhang
The paper identifies two CRISPR-Cas VI-B systems with Cas13b and characterizes their RNA interference activity and regulation by Csx27 and Csx28.
bioRxiv · Dec 9, 2016Microbiology