Author

P. F. Leadlay

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Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1

Frequent Co-Authors

A. Reva· 1 shared C. Huang· 1 shared F. Huang· 1 shared F. J. Leeper· 1 shared G. Sun· 1 shared J. Guo· 1 shared J. Zhou· 1 shared M. V. B. Dias· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMicrobiology

A. Reva

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1 paper

Recent·Most cited

Mechanistic insights into dideoxygenation in gentamicin biosynthesis

S. Li, P. d. S. Bury, F. Huang, J. Guo, G. Sun, A. Reva, C. Huang, X. Jian, Y. Li, J. Zhou, Z. Deng, F. J. Leeper, P. F. Leadlay, M. V. B. Dias, Y. Sun

The paper elucidates the dideoxygenation mechanism in gentamicin biosynthesis, showing how intermediates JI-20A and JI-20B are converted to gentamicin C complex through phosphorylation and PLP-dependent enzymatic reactions.

bioRxiv · May 12, 2021Microbiology