Phosphate Is The Third Nutrient Monitored By TOR In Candida albicans And Provides A Target For Fungal-Specific Indirect TOR Inhibition
N.-N. Liu, P. Flanagan, J. Zeng, N. Jani, M. E. Cardenas, G. P. Moran, J. R. Koehler
This study identifies Pho84 as a phosphate importer linked to TORC1 in C. albicans, showing that phosphate availability is monitored by TORC1 and that inhibiting Pho84 can indirectly target TORC1.
bioRxiv · May 27, 2017Microbiology