Author

N.-N. Liu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Pathology· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 4 Approach:experimental assay· 2 Approach:genetic perturbation / CRISPR· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

G. P. Moran· 2 shared J. R. Koehler· 2 shared K. Ryman· 2 shared M. Acosta Zaldivar· 2 shared N. Jani· 2 shared P. O. Ljungdahl· 2 shared W. Qi· 2 shared A. Besold· 1 shared

Activity by Year

2017-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersMicrobiology

G. P. Moran

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Author profile →

5 papers

Recent·Most cited

Stress- and metabolic responses of Candida albicans require Tor1 kinase N-terminal HEAT repeats

W. Qi, M. Acosta Zaldivar, P. R. Flanagan, N.-N. Liu, N. Jani, J. F. Fierro, M. T. Andres, G. P. Moran, J. R. Köhler

This study shows that the N-terminal HEAT repeats of Tor1 kinase in C. albicans are essential for stress and metabolic responses, with loss of these repeats impairing certain stress responses and metabolic adaptations.

bioRxiv · Nov 5, 2021Microbiology

Identification of microbial markers across populations in early detection of colorectal cancer

Y. Wu, N. Jiao, R. Zhu, Y. Zhang, D. Wu, A.-j. Wang, S. Fang, L. Tao, Y. Li, S. Cheng, X. He, P. Lan, C. Tian, N.-N. Liu, L. Zhu

The paper identifies microbial markers for early colorectal cancer detection across populations using meta-analysis and classifier models, achieving high diagnostic accuracy.

bioRxiv · Aug 16, 2020Pathology

Glutamate dehydrogenase (Gdh2)-dependent alkalization is dispensable for escape from macrophages and virulence of Candida albicans

F. G. S. Silao, K. Ryman, T. Jiang, M. Ward, N. Hansmann, N.-N. Liu, C. Chen, P. O. Ljungdahl

This study shows that Gdh2-dependent alkalization is not required for C. albicans to escape macrophages or maintain virulence, challenging the existing model of amino acid catabolism in phagosomes.

bioRxiv · Jan 20, 2020Microbiology

Intersection of phosphate transport, oxidative stress and TOR signalling in Candida albicans virulence

N.-N. Liu, P. Uppuluri, A. Broggi, A. Besold, K. Ryman, H. Kambara, N. Solis, V. Lorenz, W. Qi, M. Acosta Zaldivar, S. N. Emami, B. Bao, D. An, F. Bonilla, M. Sola-Visner, , J. R. Koehler

This study shows that Pho84 in Candida albicans affects virulence by modulating oxidative stress through Sod3 and TORC1 pathways.

bioRxiv · May 11, 2018Microbiology

Phosphate Is The Third Nutrient Monitored By TOR In Candida albicans And Provides A Target For Fungal-Specific Indirect TOR Inhibition

N.-N. Liu, P. Flanagan, J. Zeng, N. Jani, M. E. Cardenas, G. P. Moran, J. R. Koehler

This study identifies Pho84 as a phosphate importer linked to TORC1 in C. albicans, showing that phosphate availability is monitored by TORC1 and that inhibiting Pho84 can indirectly target TORC1.

bioRxiv · May 27, 2017Microbiology