Author

P. I. Thakore

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. Regev· 2 shared A. Hata· 1 shared A. Schnell· 1 shared C. P. Fulco· 1 shared C. Wang· 1 shared D. J. Slamon· 1 shared E. Christian· 1 shared E. Zaganjor· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

A. Regev

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Author profile →

2 papers

Recent·Most cited

The chromatin landscape of Th17 cells reveals mechanisms of diversification of regulatory and pro-inflammatory states

P. I. Thakore, A. Schnell, M. Zhao, L. Huang, Y. Hou, E. Christian, S. Zaghouani, C. Wang, V. Singh, S. Ma, V. Sankar, S. Notarbartolo, J. D. Buenrostro, F. Sallusto, N. A. Patsopoulos, , A. Regev

The paper analyzes chromatin landscapes of Th17 cell subsets to uncover regulatory mechanisms driving their heterogeneity and identifies BACH2 as a novel regulator of pathogenicity.

bioRxiv · Feb 26, 2022Immunology

Cycling cancer persister cells arise from lineages with distinct transcriptional and metabolic programs

Y. Oren, M. Tsabar, H. F. Cabanos, M. S. Cuoco, E. Zaganjor, P. I. Thakore, M. Tabaka, C. P. Fulco, S. A. Hurvitz, D. J. Slamon, G. Lahav, A. Hata, J. S. Brugge, A. Regev

The paper identifies cycling cancer persisters with distinct transcriptional and metabolic programs using a new tracing system and shows that targeting oxidative stress or metabolic reprogramming reduces their fraction.

bioRxiv · Jun 5, 2020Cancer Biology