Author

S. Zaghouani

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. Regev· 2 shared A. Schnell· 2 shared C. Wang· 2 shared A. Wagner· 1 shared C. Clish· 1 shared D. DeTomaso· 1 shared D. Puleston· 1 shared E. Christian· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersImmunology

A. Regev

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2 papers

Recent·Most cited

The chromatin landscape of Th17 cells reveals mechanisms of diversification of regulatory and pro-inflammatory states

P. I. Thakore, A. Schnell, M. Zhao, L. Huang, Y. Hou, E. Christian, S. Zaghouani, C. Wang, V. Singh, S. Ma, V. Sankar, S. Notarbartolo, J. D. Buenrostro, F. Sallusto, N. A. Patsopoulos, , A. Regev

The paper analyzes chromatin landscapes of Th17 cell subsets to uncover regulatory mechanisms driving their heterogeneity and identifies BACH2 as a novel regulator of pathogenicity.

bioRxiv · Feb 26, 2022Immunology

Metabolic and Epigenomic Regulation of Th17/Treg Balance by the Polyamine Pathway

C. Wang, A. Wagner, J. Fessler, J. Avila-Pacheco, J. Karminski, P. Thakore, S. Zaghouani, K. Pierce, L. Bod, A. Schnell, D. DeTomaso, N. Ron-Harel, M. Haigis, D. Puleston, E. Pearce, , V. Kuchroo

The paper identifies the polyamine pathway as a regulator of Th17/Treg balance, showing its impact on inflammation and T cell phenotype.

bioRxiv · Jan 23, 2020 · PreprintImmunology