Cyclophilin A regulates protein phase separation and mitigates haematopoietic stem cell aging
L. Maneix, P. Iakova, S. E. Moree, J. C. K. King, D. B. Sykes, C. T. Hill, B. Saez, E. Spooner, D. S. Krause, E. Sahin, B. C. Berk, D. T. Scadden, A. Catic
This study identifies Cyclophilin A as a key regulator of protein phase separation and shows its role in mitigating haematopoietic stem cell aging.
bioRxiv · Feb 24, 2021Cell Biology