Cell BiologybioRxivPreprint
The Structural Flexibility of MAD1 Facilitates the Assembly of the Mitotic Checkpoint Complex
C. Chen, V. Piano, A. Alex…·A. Joglekar
This study shows that structural flexibility in MAD1's hinge region is crucial for efficient MCC assembly and SAC signaling, with implications for understanding mitotic checkpoint function.
DOI 10.1101/2022.06.29.498198