P. J. Novick

Exploring the consequences of redirecting an exocytic Rab onto endocytic vesicles.

This study redirects an exocytic Rab, Sec4, to endocytic vesicles and shows that cells tolerate this misdirection without significant growth defects.

Double NPY motifs at the N-terminus of Sso2 synergistically bind Sec3 to promote membrane fusion

This study identifies dual-site interactions between Sso2 and Sec3 that drive secretory vesicle fusion in yeast.