Molecular determinants of dynamic protein-protein interactions in the functional cycle of the membrane protein DsbD
L. S. Stelzl, P. Kritsiligkou, A. R. Mehdipour, A. J. Baldwin, S. J. Ferguson, D. A. I. Mavridou, M. S. P. Sansom, C. Redfield
This study identifies molecular determinants of dynamic protein-protein interactions in DsbD using NMR, molecular dynamics, and AlphaFold modeling, revealing redox-state-dependent binding and a putative thioredoxin binding site.
bioRxiv · Sep 7, 2022 · PreprintBiophysics