D. A. I. Mavridou

This study identifies molecular determinants of dynamic protein-protein interactions in DsbD using NMR, molecular dynamics, and AlphaFold modeling, revealing redox-state-dependent binding and a putative thioredoxin binding site.

This paper shows that disrupting disulfide bond formation in Gram-negative bacteria sensitizes them to antibiotics by impairing resistance proteins.

This study reveals that colistin kills bacteria by targeting lipopolysaccharide in the cytoplasmic membrane, not the outer membrane, and shows that murepavadin can enhance its efficacy.

The paper develops a droplet printing method to study bacterial ecology by manipulating spatial arrangements of E. coli strains and shows how micron-scale structure affects competition and coexistence.

This study shows how oxidation of cysteine thiols to a disulfide bond in DsbD introduces local frustration, disrupting the cap-loop structure and enabling loop opening during its catalytic cycle.

The paper identifies novel structural components that stabilize short TssA-containing T6SSs, leading to distinct firing behaviors and aggression strategies in bacteria.

The paper uses TraDIS to identify T6SS toxins in Pseudomonas aeruginosa, finding Tse8 targets bacterial protein synthesis by disrupting the transamidosome complex.