L. S. Stelzl

This study introduces a method to assemble ssRNA structures using hierarchical chain growth, showing agreement with experimental data and improving accuracy with Bayesian refinement.

This study identifies molecular determinants of dynamic protein-protein interactions in DsbD using NMR, molecular dynamics, and AlphaFold modeling, revealing redox-state-dependent binding and a putative thioredoxin binding site.

This study presents cryo-EM structures of human TSEN with pre-tRNAs, revealing substrate recognition mechanisms and structural basis of PCH-associated mutations.

This study uses molecular simulations to investigate how aromatic residues affect the conformation and phase behavior of hnRNPA1's low-complexity domain, revealing their role in condensation and critical temperature changes.

This study shows that hyperphosphorylation of TDP-43 reduces its phase separation and aggregation, suggesting it may act as a protective mechanism against neurodegeneration.

This study uses a computational method to model the structural ensemble of tau K18, showing how local structure influences global conformational states and disease-related aggregation.

This paper develops a coarse-grained model to simulate FUS protein condensates and maps their phase behavior by adjusting interaction strengths.

This study shows how oxidation of cysteine thiols to a disulfide bond in DsbD introduces local frustration, disrupting the cap-loop structure and enabling loop opening during its catalytic cycle.

This study uses molecular dynamics simulations to generate diverse structural ensembles of intrinsically disordered proteins at atomic resolution, capturing both local and global structures.