Author

P. L. Schwartzberg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Buffone· 1 shared A. J. Hedges· 1 shared B. Huang· 1 shared C. Massoue· 1 shared C. Wülfing· 1 shared D. A. Hammer· 1 shared D. Alibhai· 1 shared D. Blumenthal· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

A. Buffone

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2 papers

Recent·Most cited

LFA-1 signals to promote actin polymerization and upstream migration in T cells

N. H. Roy, S. H. Kim, A. Buffone, D. Blumenthal, B. Huang, S. Agarwal, P. L. Schwartzberg, D. A. Hammer, J. K. Burkhardt

This study shows that LFA-1 signaling, but not VLA-4, drives cytoskeletal changes enabling T cells to migrate upstream against shear flow.

bioRxiv · Apr 29, 2020Cell Biology

Transient protein accumulation at the center of the T cell antigen presenting cell interface drives efficient IL-2 secretion

D. J. Clark, L. E. McMillan, S. L. Tan, G. Bellomo, C. Massoue, H. Thompson, L. Mykhaylechko, D. Alibhai, X. Ruan, K. L. Singleton, M. Du, A. J. Hedges, P. L. Schwartzberg, P. Verkade, R. F. Murphy, C. Wülfing

The paper investigates the role of the central supramolecular signaling cluster (cSMAC) in T cell activation by manipulating adaptor proteins and showing its impact on IL-2 secretion.

bioRxiv · Feb 4, 2019Immunology