Author

D. J. Clark

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Assay:imaging· 1 Assay:proteomics· 1

Frequent Co-Authors

A. J. Crawford· 1 shared A. J. Hedges· 1 shared A. Roy· 1 shared B. A. Starich· 1 shared B. Su· 1 shared C. J. Hass· 1 shared C. Liu· 1 shared C. Massoue· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperCancer Biology

A. J. Crawford

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Author profile →

3 papers

Recent·Most cited

Uneven terrain treadmill walking in younger and older adults

R. J. Downey, N. Richer, R. Gupta, C. Liu, E. M. Pliner, A. Roy, J. Hwang, D. J. Clark, C. J. Hass, T. M. Manini, R. D. Seidler, D. P. Ferris

This study tests how varying treadmill terrain unevenness affects gait kinematic variability and perceived stability in younger and older adults.

bioRxiv · Mar 1, 2022Bioengineering

E-cadherin interacts with EGFR resulting in hyper-activation of ERK in multiple models of breast cancer

G. C. Russo, A. J. Crawford, D. J. Clark, J. Cui, R. Carney, M. N. Karl, B. Su, B. A. Starich, T.-S. Lih, P. Kamat, Q. Zhang, P.-h. Wu, M.-H. Lee, H. S. Leong, V. W. Rebecca, , D. Wirtz

This study shows E-cadherin interacts with EGFR to hyper-activate ERK, promoting proliferation in breast cancer models and identifying a potential therapeutic target.

bioRxiv · Nov 4, 2020Cancer Biology

Transient protein accumulation at the center of the T cell antigen presenting cell interface drives efficient IL-2 secretion

D. J. Clark, L. E. McMillan, S. L. Tan, G. Bellomo, C. Massoue, H. Thompson, L. Mykhaylechko, D. Alibhai, X. Ruan, K. L. Singleton, M. Du, A. J. Hedges, P. L. Schwartzberg, P. Verkade, R. F. Murphy, C. Wülfing

The paper investigates the role of the central supramolecular signaling cluster (cSMAC) in T cell activation by manipulating adaptor proteins and showing its impact on IL-2 secretion.

bioRxiv · Feb 4, 2019Immunology