Author

P. Lesage

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:yeast· 1

Frequent Co-Authors

A. Asif-Laidin· 1 shared A. Barkova· 1 shared A. BONNET· 1 shared A. Cormier· 1 shared A. Saib· 1 shared A. Zamborlini· 1 shared B. Kim· 1 shared c. Chagneau· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBiochemistry

A. Asif-Laidin

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2 papers

Recent·Most cited

A proteomic screen of Ty1 integrase partners identifies the protein kinase CK2 as a regulator of Ty1 retrotransposition

A. Barkova, I. Adhya, C. Conesa, A. Asif-Laidin, A. BONNET, E. Rabut, c. Chagneau, P. Lesage, J. Acker

The paper identifies CK2 kinase as a regulator of Ty1 retrotransposition through proteomic screening and shows CK2 inhibits Ty1 mobility by repressing transcription.

bioRxiv · Jul 13, 2022Biochemistry

SUMOylation of SAMHD1 at Lysine 595 is required for HIV-1 restriction in non-cycling cells

C. Martinat, A. Cormier, J. Tobaly-Tapiero, N. Palmic, N. Casartelli, S. A. Coggins, J. Buchrieser, M. Persaud, F. Diaz-Griffero, L. Espert, G. Bossis, P. Lesage, O. Schwartz, B. Kim, F. Margottin, , A. Zamborlini

This study shows that SUMOylation of SAMHD1 at K595 is necessary for its antiviral activity in non-cycling cells, independent of its dNTPase function.

bioRxiv · Jun 4, 2020Microbiology