A. Droit

Myelin-reactive B cells exacerbate the severity of CD4+ T cell-driven CNS autoimmunity in an IL-23-dependent manner.

This study shows that MOG-specific B cells worsen CD4+ T cell-driven CNS autoimmunity by promoting Th17 and Tph cell accumulation via IL-23.

Resolving the temporal splenic proteome during fungal infection for discovery of putative dual perspective biomarker signatures

This study uses proteomics to analyze the temporal spleen proteome during Cryptococcus neoformans infection in mice, identifying immune and pathogen biomarkers.

Concomitant effects of orchiectomy and intermittent hypoxia onhepatic oxidative stress, expression of flavin-containingmonooxygenases and transcriptomic profile in mice.

This study examines how orchiectomy and intermittent hypoxia interact to affect hepatic oxidative stress and gene expression in mice.

Male sex chromosomal complement exacerbates the pathogenicity of Th17 cells in a chronic model of CNS autoimmunity.

This study shows male sex chromosomal complement increases Th17 cell pathogenicity in CNS autoimmunity, independent of hormones, through downregulation of Jarid1c.

Fast and accurate bacterial species identification in biological samples using LC-MS/MS mass spectrometry and machine learning

This paper develops a method using LC-MS/MS and machine learning to rapidly identify bacterial species in clinical samples without culture, achieving 97% accuracy for UTI pathogens.