Author

P. N. Barlow

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Research Focus:protein folding & dynamics· 2 Approach:statistical model· 2 Approach:deep learning· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

A. A. Gupta· 2 shared J. Michel· 2 shared A. De Simone· 1 shared A. J. Baldwin· 1 shared A. Mey· 1 shared A. N. Hulme· 1 shared C. Georgiou· 1 shared C. Ioannidis· 1 shared

Activity by Year

2019-2021 · peak 1/yr

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10 top collaborators · 38 mutual co-author links

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2 shared papersBiophysics

A. A. Gupta

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2 papers

Recent·Most cited

Energetics of a protein disorder-order transition in small molecule recognition

C. Mendoza-Martinez, M. Papadourakis, s. llabres, A. A. Gupta, P. N. Barlow, J. Michel

The paper investigates how a small molecule modulates a protein disorder-to-order transition, showing AM-7209 preferentially stabilizes ordered lid conformations in MDM2 compared to Nutlin-3a.

bioRxiv · Aug 5, 2021Biophysics

Dynamic design: manipulation of millisecond timescale motions on the energy landscape of Cyclophilin A

J. Juarez-Jimenez, A. A. Gupta, G. Karunanithy, A. Mey, C. Georgiou, C. Ioannidis, A. De Simone, P. N. Barlow, A. N. Hulme, M. D. Walkinshaw, A. J. Baldwin, J. Michel

The paper uses accelerated MD and MSM to study millisecond timescale conformational dynamics of CypA, identifying key states and validating predictions with NMR.

bioRxiv · Sep 17, 2019Biophysics