Author

C. Georgiou

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biophysics· 2 Bioengineering· 1 Cancer Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Organism:human· 2 Research Focus:protein folding & dynamics· 2 Assay:protein structure· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

J. Michel· 2 shared M. D. Walkinshaw· 2 shared A. A. Gupta· 1 shared A. De Simone· 1 shared A. J. Baldwin· 1 shared A. Mey· 1 shared A. N. Hulme· 1 shared C. Christodoulidou· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiophysics

J. Michel

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

The effect of Vitamin D (1,25-(OH)2-D3) on human theca and granulosa cell function.

H. P. Seaward Brain, C. Georgiou, H. D. Mason, S. Rice

This study investigates how Vitamin D deficiency affects ovarian cell function and shows that local production of 1,25-(OH)2-D3 in the ovary may counteract systemic deficiency.

bioRxiv · Jun 16, 2023Physiology

Dynamic regulation of hierarchical heterogeneity in Acute Myeloid Leukemia serves as a tumor immunoevasion mechanism

C. Pospori, W. Grey, S. Gonzalez-Anton, S. V. Gibson, C. Georgiou, F. Birch, G. Stevens, T. Williams, R. Khorshed, M. L. R. Haltalli, M.-N. Skoufou-Papoutsaki, K. Sloan, H. H. Encabo, J. Hopkins, C. Christodoulidou, , C. L. Lo Celso

The paper shows that hierarchical heterogeneity in AML cells, regulated by immune responses, contributes to disease progression through PDL1 upregulation and dynamic balance between proliferation and immunosuppression.

bioRxiv · Dec 21, 2020 · PreprintCancer Biology

Stretchable Composite Acoustic Transducer for Wearable Monitoring of Vital Signs

Y. Cotur, M. Kasimatis, M. Kaisti, S. Olenik, C. Georgiou, F. Guder

This paper introduces a stretchable acoustic transducer for non-contact monitoring of heart and respiratory patterns in humans and furry animals.

bioRxiv · Dec 14, 2019Bioengineering

Dynamic design: manipulation of millisecond timescale motions on the energy landscape of Cyclophilin A

J. Juarez-Jimenez, A. A. Gupta, G. Karunanithy, A. Mey, C. Georgiou, C. Ioannidis, A. De Simone, P. N. Barlow, A. N. Hulme, M. D. Walkinshaw, A. J. Baldwin, J. Michel

The paper uses accelerated MD and MSM to study millisecond timescale conformational dynamics of CypA, identifying key states and validating predictions with NMR.

bioRxiv · Sep 17, 2019Biophysics

Pushing The Limits Of Detection Of Weak Binding Using Fragment Based Drug Discovery: Identification Of New Cyclophilin Binders

C. Georgiou, I. W. McNae, M. A. Wear, H. Ioannidis, J. Michel, M. D. Walkinshaw

This paper identifies novel cyclophilin binders using fragment-based drug discovery and combines X-ray diffraction, SPR, and MD simulations to better characterize weak binding events.

bioRxiv · Jun 15, 2017Biophysics