Author

P. Newton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 3 Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Approach:deep learning· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:whole-genome sequencing· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1

Frequent Co-Authors

A. Kumar· 2 shared M. Vongsouvath· 2 shared A. Akovantseva· 1 shared A. C. Myall· 1 shared A. Chanthongthip· 1 shared A. D. Kurenkova· 1 shared A. Dubot-Peres· 1 shared A. E. Snaith· 1 shared

Activity by Year

2019-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersMicrobiology

A. Kumar

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Author profile →

6 papers

Recent·Most cited

The highly diverse and complex plasmid population found in Escherichia coli colonising travellers to Laos and their role in antimicrobial resistance gene carriage

A. E. Snaith, S. J. Dunn, R. A. Moran, P. Newton, D. Dance, V. Davong, E. Keunzli, A. Kantele, J. Corander, A. McNally

This study characterizes the diverse plasmid population in ESBL-producing E. coli from travellers to Laos, revealing AMR gene carriage and potential for global AMR spread.

bioRxiv · Aug 22, 2022 · PreprintMicrobiology

Bernstein polynomial approximation of fixation probability in finite population evolutionary games

J. Park, P. Newton

The paper approximates fixation probability in finite population evolutionary games using Bernstein polynomials, showing better efficiency in strong selection regimes.

bioRxiv · Aug 5, 2022Evolutionary Biology

Deep proteomics network and machine learning analysis of human cerebrospinal fluid in Japanese encephalitis virus infection

T. Bharucha, B. Gangadharan, A. Kumar, A. C. Myall, N. Ayhan, B. Pastorino, A. Chanthongthip, M. Vongsouvath, M. Mayxay, O. Sengvilaipaseuth, S. Rattanavong, D. P. O'Brien, I. Vendrell, R. Fischer, B. Kessler, , SEAe collaborators

This study identifies a ten-protein diagnostic signature for Japanese encephalitis virus infection in cerebrospinal fluid with >99% accuracy using proteomics and machine learning.

bioRxiv · Jun 19, 2022Microbiology

Secondary ossification center induces and protects growth plate structure

M. Xie, P. Goldin, A. N. Herdina, J. Estefa, E. Medvedeva, L. Li, P. Newton, S. Kotova, B. Shavkuta, A. Saxena, L. Shumate, B. Metscher, K. Groschmidt, S. Nishimori, A. Akovantseva, , A. S. Chagin

This study identifies the secondary ossification center's role in protecting growth plate hypertrophic chondrocytes from mechanical stress during terrestrial adaptation.

bioRxiv · Sep 1, 2020Evolutionary Biology

The role of synergy and antagonism in designing multidrug adaptive chemotherapy schedules

P. Newton, Y. Ma

This paper develops an evolutionary game theory model to design two-drug adaptive chemotherapy schedules that mitigate chemoresistance by leveraging antagonistic drug interactions.

bioRxiv · May 13, 2020Evolutionary Biology

Genomic surveillance for hypervirulence and multi-drug resistance in invasive Klebsiella pneumoniae from south and southeast Asia.

K. L. Wyres, T. N. Nguyen, M. M. Lam, L. M. Judd, N. van Vinh Chau, D. A. Dance, M. Ip, A. Karkey, C. L. Ling, T. Miliya, P. Newton, L. Nguyen, A. Sengduangphachanh, P. Turner, B. Veeraraghavan, , K. E. Holt

This study identifies diverse antimicrobial resistant and hypervirulent Klebsiella pneumoniae strains in South and Southeast Asia, highlighting the convergence of AMR and virulence genes.

bioRxiv · Feb 26, 2019Microbiology