R. A. Moran

Differential development of antibiotic resistance and virulence between Acinetobacter species

This study compares antibiotic resistance and virulence between Acinetobacter lwoffii and A. baumannii, finding A. lwoffii has fewer resistance genes, more DNA defense systems, and reduced ability to develop resistance.

Non-antibiotic pharmaceuticals exhibit toxicity against Escherichia coli at environmentallyrelevant concentrations with no evolution of cross-resistance to antibiotics

This study shows non-antibiotic pharmaceuticals inhibit E. coli growth at environmental concentrations without promoting cross-resistance to antibiotics.

Growth in a biofilm promotes conjugation of a blaNDM-1-bearing plasmid between Klebsiella pneumoniae strains

This study shows biofilm growth significantly increases conjugative transfer of a carbapenem resistance plasmid in K. pneumoniae without fitness costs.

Extended-spectrum beta-lactamase genes traverse the Escherichia coli populations of ICU patients, staff and environment.

This study tracks the spread of ESBL-EC in an ICU, finding distinct patient and environmental isolates but shared plasmid lineages carrying blaCTX-M genes.

Integrons, plasmids, and resistance genes in equine faecal bacteria

This study examines how domestication and antimicrobial treatment affect the prevalence of class 1 integrons and antibiotic resistance genes in equine gut bacteria, identifying distinct bacterial taxa and mobile genetic elements associated with these factors.

The highly diverse and complex plasmid population found in Escherichia coli colonising travellers to Laos and their role in antimicrobial resistance gene carriage

This study characterizes the diverse plasmid population in ESBL-producing E. coli from travellers to Laos, revealing AMR gene carriage and potential for global AMR spread.

GR13-type plasmids in Acinetobacter potentiate the accumulation and horizontal transfer of diverse accessory genes

This study characterizes GR13 plasmids in Acinetobacter, showing their capacity to accumulate and horizontally transfer diverse accessory genes through dif modules and insertion sequences.

Microbiota analysis of rural and urban surface waters and sediments in Bangladesh identifies human waste as driver of antibiotic resistance

The paper analyzes antibiotic resistance genes in surface waters and sediments from rural and urban areas in Bangladesh, finding that urban areas have higher levels of resistance genes linked to human gut bacteria.