Author

P. Ortega

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Aguilera· 1 shared A. Becker· 1 shared A. Cheung· 1 shared A. Sanchez· 1 shared B. Gomez-Gonzalez· 1 shared B. Pfander· 1 shared C. Durfee· 1 shared C. Kurat· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

A. Aguilera

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Author profile →

2 papers

Recent·Most cited

Mesoscale DNA Features Impact APOBEC3A and APOBEC3B Deaminase Activity and Shape Tumor Mutational Landscapes

A. Sanchez, P. Ortega, R. Sakhtemani, L. Manjunath, S. Oh, E. Bournique, A. Becker, K. Kim, C. Durfee, N. A. Temiz, X. Chen, R. Harris, M. Lawrence, R. Buisson

This study identifies how mesoscale DNA features influence APOBEC3A and APOBEC3B deaminase activity and their impact on tumor mutational landscapes.

bioRxiv · Aug 2, 2023Biochemistry

A CDK-regulated chromatin segregase promoting chromosome replication

E. Chacin, P. Bansal, K.-U. Reusswig, L. Diaz-Santin, P. Ortega, P. Vizjak, B. Gomez-Gonzalez, F. Mueller-Planitz, A. Aguilera, B. Pfander, A. Cheung, C. Kurat

This study identifies Yta7 as a CDK-regulated chromatin segregase that facilitates chromosome replication by disassembling nucleosomes during S phase.

bioRxiv · Nov 20, 2020Biochemistry