Cancer BiologybioRxiv
Detection of PD-L1-expressing myeloid cell clusters in the hyaluronan-enriched stroma in tumor tissue and tumor-draining lymph nodes
P. R. Dominguez-Gutierrez, E. Kwenda, W. Donelan…·S. Kusmartsev
The paper identifies HA-enriched stromal clusters containing PD-L1+ macrophages in tumor tissue and lymph nodes, linking HA production to immunosuppressive PD-L1 expression.