W. Donelan

Detection of PD-L1-expressing myeloid cell clusters in the hyaluronan-enriched stroma in tumor tissue and tumor-draining lymph nodes

The paper identifies HA-enriched stromal clusters containing PD-L1+ macrophages in tumor tissue and lymph nodes, linking HA production to immunosuppressive PD-L1 expression.

Identification of Hyal2-expressing tumor-associated myeloid cells in cancer: implications for cancer-related inflammation through enhanced hyaluronan degradation

This study identifies Hyal2-expressing tumor-associated myeloid cells in bladder cancer that enhance HA degradation, leading to LMW-HA accumulation and inflammation.