Author

P. R. Murphy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Organism:zebrafish· 1

Frequent Co-Authors

A. B. Lyons· 2 shared A. S. Flies· 2 shared G. M. Woods· 2 shared J. M. Darby· 2 shared P. R. Lennard· 2 shared T. L. Pinfold· 2 shared A. L. Patchett· 1 shared C. E. B. Ong· 1 shared

Activity by Year

2020-2020 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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2 shared papersImmunology

A. B. Lyons

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Tasmanian devil CD28 and CTLA4 capture CD80 and CD86 from adjacent cells

C. Wong, J. M. Darby, P. R. Murphy, T. L. Pinfold, P. R. Lennard, G. M. Woods, A. B. Lyons, A. S. Flies

This study shows Tasmanian devil CTLA4 and CD28 can capture CD80 and CD86 from adjacent cells, similar to other species, suggesting potential for checkpoint immunotherapy in divergent species.

bioRxiv · Jun 11, 2020Immunology

Peripheral tolerance checkpoints imposed by ubiquitous antigen expression limit antigen-specific B-cell responses under strongly immunogenic conditions

J. F. brooks, P. R. Murphy, J. E. Barber, J. W. Wells, R. Steptoe

The paper investigates how peripheral tolerance checkpoints limit self-reactive B-cell responses during bystander inflammation using a strong adjuvant and new detection tools.

bioRxiv · Mar 10, 2020Immunology

A novel system to map protein interactions reveals evolutionarily conserved immune evasion pathways on transmissible cancers

A. S. Flies, J. M. Darby, P. R. Lennard, P. R. Murphy, C. E. B. Ong, T. L. Pinfold, A. B. Lyons, G. M. Woods, A. L. Patchett

The paper develops a reagent method to study immune checkpoints in non-model species and identifies conserved immune evasion pathways in transmissible cancers.

bioRxiv · Jan 3, 2020Immunology