Structural basis for tunable control of actin dynamics by myosin-15 in mechanosensory stereocilia
R. Gong, F. Jiang, Z. G. Moreland, M. J. Reynolds, S. Espinosa de los Reyes, P. S. Gurel, A. Shams, M. R. Bowl, J. E. Bird, G. M. Alushin
This paper presents cryo-EM structures of myosin-15 bound to F-actin, revealing how mutations affect actin polymerization and stereocilia elongation.
bioRxiv · Jul 9, 2021Biophysics