Author

P. S. Olofsson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

S. G. Malin· 3 shared J. Metso· 2 shared M. Jauhiainen· 2 shared S. Hellberg· 2 shared V. Manfe· 2 shared V. S. Shavva· 2 shared A. Farnert· 1 shared A. Franco-Cereceda· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersImmunology

S. G. Malin

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Author profile →

3 papers

Recent·Most cited

Kupffer cells dictate hepatic responses to the atherogenic dyslipidemic insult

S. Hellberg, O. Ahmed, Y. Zhang, G. Di Nunzio, H. M. Bjorck, R. Francis, L. Fagerberg, A. Gistera, X. Zhang, J. Metso, V. Manfe, Y. Soto, A. Franco-Cereceda, P. Eriksson, M. Jauhiainen, , S. G. Malin

The paper investigates how Kupffer cells in the liver respond to atherogenic dyslipidemia and show they regulate systemic atherosclerosis by restraining lipoproteins and secreting pro-atherosclerotic factors.

bioRxiv · Oct 13, 2022 · PreprintImmunology

Identification and Characterization of Human Activation-Induced ChAT+CD4+ T Cells

L. Tarnawski, A. L. Gallina, E. J. Kort, V. S. Shavva, Z. Zhuge, D. Martinez Enguita, M. Weiland, A. S. Caravaca, S. Schmidt, F.-H. Wang, A. Farnert, E. Weitzberg, M. Gustafsson, M. Eberhardson, H. Hult, , P. S. Olofsson

The paper identifies and characterizes human ChAT+CD4+ T cells, showing their induction by activation and association with vasorelaxation and improved survival in critically ill patients.

bioRxiv · Apr 27, 2021 · PreprintImmunology

Alternate models of acute dyslipidemia reveal divergent pathways upon atherosclerosis initiation

S. Hellberg, V. s. Shavva, J. Metso, G. Chen, Q.-Z. Li, V. Manfe, P. S. Olofsson, M. Jauhiainen, C. J. Binder, S. G. Malin

This study uses two novel mouse models to show that different pathways lead to atherogenesis, with APOE inhibiting inflammation and CD8 T cells regulating aortic response.

bioRxiv · Sep 2, 2020 · PreprintPhysiology