Author

P. S. Randolph

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 2

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 3 Approach:experimental assay· 3 Approach:deep learning· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

S. M. Stagg· 4 shared J. H. Mendez· 2 shared A. K. Paravastu· 1 shared A. Mehrani· 1 shared A. S. Roband· 1 shared B. E. Bammes· 1 shared C. Guo· 1 shared H.-X. Zhou· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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4 shared papersBiochemistry

S. M. Stagg

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Author profile →

4 papers

Recent·Most cited

Structural Model for Self-Limiting β-strand Arrangement Within an Alzheimer's Amyloid-β Oligomer

Y. Gao, R. Prasad, P. S. Randolph, J. O. Watzlawik, A. S. Roband, C. Guo, S. M. Stagg, H.-X. Zhou, T. L. Rosenberry, A. K. Paravastu

The paper presents a structural model of an Alzheimer's Aβ42 oligomer based on solid-state NMR and cryo-EM data, explaining its stability and ion permeability.

bioRxiv · Dec 6, 2022 · PreprintBiochemistry

Characterizing the Resolution and Throughput of the Apollo Direct Electron Detector

R. Peng, X. Fu, J. H. Mendez, P. S. Randolph, B. E. Bammes, S. M. Stagg

The paper evaluates the Apollo direct electron detector's performance in cryo-EM, showing high-resolution reconstructions across different dose rates and sample sizes.

bioRxiv · Sep 16, 2022Biochemistry

Reconstruction of Average Subtracted Tubular Regions (RASTR) Enables Structure Determination of Tubular Filaments by Cryo-EM

P. S. Randolph, S. M. Stagg

This paper introduces RASTR, a method for 3D reconstruction of tubular structures without symmetry assumptions, and evaluates it on simulated and experimental data.

bioRxiv · Sep 18, 2019Biophysics

Throughput and Resolution with a Next Generation Direct Electron Detector

J. H. Mendez, A. Mehrani, P. S. Randolph, S. M. Stagg

This paper evaluates a new direct electron detector (DE64) for cryo-electron microscopy, showing that counting mode provides better reconstruction resolution per unit time despite lower throughput.

bioRxiv · May 3, 2019Biophysics