Engineered chimeric T cell receptor fusion construct (TRuC)-expressing T cells prevent translational shutdown in SARS-CoV-2-infected cells
I. Godbole, K. Ciminski, O. S. Yousefi, S. Pathan-Chhatbar, D. Saltukoglu, N. Vesper, P. Salavei, J. Strietz, N. Gensch, M. Reth, M. Schwemmle, W. W. Schamel
Engineered TRuC T cells recognize and kill SARS-CoV-2-infected cells without causing cytotoxicity, rescuing translational shutdown.
bioRxiv · Jun 25, 2021 · PreprintBioengineering