Breast cancer stem cell-derived tumors escape from γδ T cell immunosurveillance in vivo by modulating γδ T cell ligands
K. Raute, J. Strietz, G. Andrieux, O. S. Thomas, K. M. Kistner, M. Zintchenko, P. Aichele, H. Zhou, W. Weber, M. Boerries, M. Swamy, J. Maurer, S. Minguet
This study shows that breast cancer stem cells escape γδ T cell immunosurveillance by losing key ligands and antigens, and that this escape can be reversed with Zoledronate or IFN- treatment.
bioRxiv · Apr 4, 2022Immunology