Author

W. W. Schamel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Organism:mouse· 1

Frequent Co-Authors

S. Minguet· 2 shared A. Plach· 1 shared A.-M. Schaffer· 1 shared B. Salzer· 1 shared D. H. Busch· 1 shared D. Saltukoglu· 1 shared G. J. Fiala· 1 shared H. Stockinger· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersImmunology

S. Minguet

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

TCR/CD3-based synthetic antigen receptors (TCC) convey superior antigen sensitivity combined with high fidelity of activation

T. Peters, V. Muehlgrabner, R. M. H. Velasco Cardenas, R. Platzer, J. Gohring, B. Salzer, A. Plach, M. Hoehrhan, I. Doel-Perez, V. D. R. Goncalves, J. S. Farfan, M. Lehner, H. Stockinger, W. W. Schamel, K. Schober, , J. B. Huppa

This study shows TCR/CD3-based synthetic antigen receptors (TCC) have superior antigen sensitivity and activation fidelity compared to second-generation CARs.

bioRxiv · Mar 16, 2023 · PreprintImmunology

Kidins220 promotes thymic iNKT cell development by reducing TCR signals, but enhances TCR signals in splenic iNKT cells

L. A. Herr, G. J. Fiala, A.-M. Schaffer, K. Raute, R. M.-H. Velasco Cardenas, J. F. Hummel, K. Ebert, Y. Tanriver, S. Minguet, W. W. Schamel

This study shows Kidins220 modulates TCR signaling in thymic and splenic iNKT cells, promoting development in the thymus by reducing TCR signals but enhancing TCR signals in the periphery.

bioRxiv · Apr 5, 2022 · PreprintImmunology

Engineered chimeric T cell receptor fusion construct (TRuC)-expressing T cells prevent translational shutdown in SARS-CoV-2-infected cells

I. Godbole, K. Ciminski, O. S. Yousefi, S. Pathan-Chhatbar, D. Saltukoglu, N. Vesper, P. Salavei, J. Strietz, N. Gensch, M. Reth, M. Schwemmle, W. W. Schamel

Engineered TRuC T cells recognize and kill SARS-CoV-2-infected cells without causing cytotoxicity, rescuing translational shutdown.

bioRxiv · Jun 25, 2021 · PreprintBioengineering