Detection of Antibodies Against the African Parasite Trypanosoma brucei Using Synthetic glycosylphosphatidylinositol oligosaccharide fragments
M. Michel, B. Stijlemans, D. Michel, M. Garg, A. Geissner, P. Seeberger, D. Varon Silva
The paper develops synthetic glycan fragments of T. brucei GPIs to detect antibodies against the parasite, showing they elicit both IgM and IgG responses, enabling diagnostic tests for African trypanosomiasis and Nagana.
bioRxiv · Dec 31, 2023 · PreprintBiochemistry