Tannic Acid Inhibits α-Synuclein Amyloid Fibril Formation via Binding to the Monomer N-terminal Domain
J. Stoeber, J. K. Williams, P. V. Moghe, J. Baum
This study shows tannic acid inhibits α-synuclein fibril formation by binding to its N-terminal domain, with pH dependence observed through NMR, AFM, and ThT assays.
bioRxiv · May 26, 2021 · PreprintBiochemistry