S. K. Libutti

Development of a novel, pan-variant aerosol intervention for COVID-19

This paper reports preclinical development and evaluation of aerosolized soluble recombinant human ACE2 (APN01) as a COVID-19 intervention.

Apropos of Universal Epitope Discovery for COVID-19 Vaccines: A Framework for Targeted Phage Display-Based Delivery and Integration of New Evaluation Tools

The paper describes a framework using targeted phage display to identify conserved epitopes on the SARS-CoV-2 Spike protein for universal vaccine development.

Tumor-targeted delivery of childhood vaccine recall antigens by attenuated Listeria reduces pancreatic cancer

This study shows that delivering a childhood vaccine antigen via attenuated Listeria improves immunotherapy for pancreatic cancer by converting cold tumors into hot tumors and enhancing T cell activity.

Extracellular vesicle molecular signatures characterize metastatic dynamicity in ovarian cancer

This study identifies a 7-gene extracellular vesicle signature associated with ovarian cancer metastasis but lacks a definitive signature due to limited sample size.

Design and proof-of-concept for targeted phage-based COVID-19 vaccination strategies with a streamlined cold-free supply chain

This paper designs and evaluates phage-based and AAVP-based vaccination strategies for SARS-CoV-2 that induce systemic antibody responses in mice, with potential for a cold-free supply chain.