Author

P. Venkatesh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Biochemistry· 1 Ecology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:protein design· 2 Assay:protein structure· 2 Approach:benchmark study· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

D. Baker· 2 shared G. R. Lee· 2 shared X. Li· 2 shared A. Chamanzar· 1 shared A. Datey· 1 shared A. H.-W. Yeh· 1 shared A. Hitchcock· 1 shared A. N. Hoofnagle· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersBiochemistry

D. Baker

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Generalized Biomolecular Modeling and Design with RoseTTAFold All-Atom

R. Krishna, J. Wang, W. Ahern, P. Sturmfels, P. Venkatesh, I. Kalvet, G. R. Lee, F. S. Morey-Burrows, I. Anishchenko, I. R. Humphreys, R. McHugh, D. Vafeados, X. Li, G. A. Sutherland, A. Hitchcock, , D. Baker

This paper introduces RFAA and RFdiffusionAA, models that can predict and design complex biomolecular assemblies including proteins, nucleic acids, small molecules, and covalent modifications.

bioRxiv · Oct 9, 2023Biochemistry

De novo design of high-affinity protein binders to bioactive helical peptides

S. Vazquez Torres, P. J. Y. Leung, I. D. Lutz, P. Venkatesh, J. L. Watson, F. Hink, H.-H. Huynh, A. H.-W. Yeh, D. Juergens, N. R. Bennett, A. N. Hoofnagle, E. Huang, M. J. MacCoss, M. Exposit, G. R. Lee, , D. Baker

This paper designs high-affinity protein binders for bioactive helical peptides using deep learning and generative models, achieving picomolar affinity without experimental optimization.

bioRxiv · Dec 10, 2022 · PreprintBioengineering

Understanding pigeon pea (Cajanus cajan) production conditions, stakeholders preferences for varietal traits and their implications for breeding programmes in India

I. Fromm, A. Singh, P. Venkatesh, H. Tewari, R. Padaria, U. Egger

The paper assesses farmers' and consumers' preferences for pigeon pea traits and production constraints in India to inform breeding programs.

bioRxiv · Jun 8, 2020 · PreprintEcology

A simple method to determine the elimination half-life of drugs displaying noncumulative toxicity

D. Nagarajan, P. Venkatesh, C. Thakur, A. Datey, N. Chandra, D. Chakravortty

This paper introduces TOXHL, a method to determine the elimination half-life of drugs with noncumulative toxicity using survival outcomes from three experiments.

bioRxiv · Sep 8, 2019 · PreprintPharmacology & Toxicology

An algorithm for automated, noninvasive detection of cortical spreading depolarizations based on EEG simulations

A. Chamanzar, S. George, P. Venkatesh, M. Chamanzar, L. Shutter, J. Elmer, P. Grover

This paper introduces an algorithm for detecting cortical spreading depolarizations from EEG signals using simulations and validates it on synthetic data.

bioRxiv · Aug 16, 2018Bioengineering