Structural basis of main proteases of coronavirus bound to drug candidate PF-07321332
J. Li, C. Lin, X. Zhou, F. Zhong, P. Zeng, H. Jiang, Y. Yang, P. McCormick, Y. Fu, J. Zhang
This study reports crystal structures of SARS-CoV-2, SARS-CoV, and MERS-CoV main proteases bound to PF-07321332, revealing conserved ligand-binding sites and insights into inhibitor mechanism.
bioRxiv · Nov 5, 2021Biophysics