Substrate-induced modulation of protein-protein interactions within human mitochondrial cytochrome P450-dependent system
Evgeniy O. Yablokov, Tatsiana A. Sushko, Leonid A. Kaluzhskiy, Anton Kavaleuski, Yuri V. Mezentsev, P.V. Ershov, Andrei A. Gilep, Alexis S. Ivanov, Natallia V. Strushkevich
The paper investigates how steroid substrates modulate protein-protein interactions between adrenodoxin and mitochondrial CYP11s, revealing isoform-specific effects on complex formation and stability.
The Journal of Steroid Biochemistry and Molecular Biology · Nov 30, 2020Peer-reviewedMolecular Biology