Author

Natallia V. Strushkevich

Skolkovo Institute of Science and TechnologyORCID 0000-0002-7096-3553Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:protein structure prediction· 2 Assay:protein structure· 1 Assay:structural biology· 1

Frequent Co-Authors

Andrei A. GilepiD· 2 shared Tatsiana A. SushkoiD· 2 shared A. I. KarputsiD· 1 shared Alexis S. IvanoviD· 1 shared Anton KavaleuskiiD· 1 shared Christopher MacCarthyiD· 1 shared Evgeniy O. YablokoviD· 1 shared Irina P. GraboveciD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBiochemistry

Andrei A. GilepORCID

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2 papers

Recent·Most cited

True-atomic-resolution insights into the interactions of antibiotic rifampicin and rifamycin derivatives with orphan CYP143 of M.tuberculosis.

Andrei A. Gilep, Christopher MacCarthy, Tatsiana Varaksa, Marianna Karpova, Irina P. Grabovec, Veronika S. Karpushenkova, Ivan Kapranov, Tatsiana A. Sushko, A. I. Karputs, Kouhei Tsumoto, Valentin I. Borshchevskiy, Natallia V. Strushkevich

The paper investigates the interaction of rifampicin and related compounds with CYP143 in M. tuberculosis, revealing binding modes and structural insights into resistance mechanisms.

bioRxiv · Dec 23, 2025 · PreprintBiochemistry

Substrate-induced modulation of protein-protein interactions within human mitochondrial cytochrome P450-dependent system

Evgeniy O. Yablokov, Tatsiana A. Sushko, Leonid A. Kaluzhskiy, Anton Kavaleuski, Yuri V. Mezentsev, P.V. Ershov, Andrei A. Gilep, Alexis S. Ivanov, Natallia V. Strushkevich

The paper investigates how steroid substrates modulate protein-protein interactions between adrenodoxin and mitochondrial CYP11s, revealing isoform-specific effects on complex formation and stability.

The Journal of Steroid Biochemistry and Molecular Biology · Nov 30, 2020Peer-reviewedMolecular Biology