Author
National Academy of Sciences of BelarusORCID 0000-0002-3621-6482Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Anastasiya Tumilovich, Evgeniy O. Yablokov, Oksana V. Gnedenko…·Alexis S. Ivanov
This study identifies direct physical interactions between CYP3A4/3A5 and SULT1E1/2A1 using SPR, activity assays, and AlphaFold2 modeling, revealing potential substrate channeling mechanisms.
Leonid A. Kaluzhskiy, Evgeniy O. Yablokov, Tatsiana Varaksa…·Alexis Ivanov
The paper identifies nine novel non-azole ligands for Mycobacterium tuberculosis CYP124 from plant and marine compounds, revealing potential for mechanism-based tuberculosis inhibitors.
Andrei A. Gilep, Christopher MacCarthy, Tatsiana Varaksa…·Natallia V. Strushkevich
The paper investigates the interaction of rifampicin and related compounds with CYP143 in M. tuberculosis, revealing binding modes and structural insights into resistance mechanisms.
Evgeniy O. Yablokov, Tatsiana A. Sushko, Leonid A. Kaluzhskiy…·Natallia V. Strushkevich
The paper investigates how steroid substrates modulate protein-protein interactions between adrenodoxin and mitochondrial CYP11s, revealing isoform-specific effects on complex formation and stability.